CLI (Command Line Interface)
/ = root directory
~ = home directory
pwd = print working directory (current directory)
clear = clear screen
ls = list stuff
-a = see all (hidden)
-l = details
cd = change directory
mkdir = make directory
touch = creates an empty file
cp = copy
cp <file> <directory> = copy a file to a directory
cp -r <directory> <newDirectory> = copy all documents from directory to new Directory * -r = recursive
rm = remove
-r = remove entire directories (no undo)
mv = move
move <file> <directory> = move file to directory
move <fileName> <newName> = rename file
echo = print arguments you give/variables
date = print current date
GitHub
- Workflow
- make edits in workspace
- update index/add files
- commit to local repo
- push to remote repository
git add . = add all new files to be tracked
git add -u = updates tracking for files that are renamed or deleted
git add -A = both of the above
- Note:
add is performed before committing
git commit -m "message" = commit the changes you want to be saved to the local copy
git checkout -b branchname = create new branch
git branch = tells you what branch you are on
git checkout master = move back to the master branch
git pull = merge you changes into other branch/repo (pull request, sent to owner of the repo)
git push = commit local changes to remote (GitHub)
Markdown
## = signifies secondary heading (bold big font)
### = signifies tertiary heading (slightly smaller font than secondary, not bold)
* = bullet list item
R Packages
- Primary location for R packages \(\rightarrow\) CRAN
available.packages() = all packages available
head(rownames(a),3) = returns first three names of a
install.packages("nameOfPackage") = install single package
install.packages(c("nameOfPackage", "nameOfPackage", "nameOfPackage") = install multiple package
- Bioconductor Packages:
source("https://bioconductor.org/biocLite.R")
biocLite() = install bioconductor packages
library(packagename) = load package
search() = see all functions in package after loading
Types of Data Science Questions
- in order of difficulty: Descriptive \(\rightarrow\) Exploratory \(\rightarrow\) Inferential \(\rightarrow\) Predictive \(\rightarrow\) Causal \(\rightarrow\) Mechanistic
- Descriptive analysis = describe set of data, interpret what you see (census, Google Ngram)
- Exploratory analysis = discovering connections (correlation does not = causation)
- Inferential analysis = use data conclusions from smaller population for the broader group
- Predictive analysis = use data on one object to predict values for another (if X predicts Y, does not = X cause Y)
- Causal analysis = how does changing one variable affect another, using randomized studies, Strong assumptions, golden standard for statistical analysis
- Mechanistic analysis = understand exact changes in variables in other variables, modeled by empirical equations (engineering/physics
Data
- Data = values of qualitative or quantitative variables, belonging to a set of items (usually population)
- Variables = measurement/characteristic of an item (qualitative vs quantitative)
- Data = not always structured, usually raw file, different formats
- Most important thing is question, then it is data
- Big data = now possible to collect data cheap, but not necessarily all useful (need the right data)
Experimental Design
- Formulate you question in advance
- Statistical inference = select subset, run experiment, calculate descriptive statistics, use inferential statistics to determine if results can be applied broadly
- [Inference] Variability = lower variability + clearer differences = decision
- [Inference] Confounding = underlying variable might be causing the correlation (sometimes called Spurious correlation)
- dealing with confounding: fix variables, stratify (all options), randomize
- [Prediction] collection observations for different variable values, build predictive functions
- similar problems of probability/sampling and confounding variables
- [Prediction] Difficult to understand where observation is from from different distributions. (size of effects important)
- [Prediction] Positive/negative statuses: True positive, false positive, false negative, true negative
- Sensitivity = Pr(positive test | disease)
- Specificity = Pr(negative test | no disease)
- Positive Predictive Value = Pr(disease | positive test)
- Negative Predictive Value = Pr(no disease | negative test)
- Accuracy = Pr(correct outcome)
- Data dredging = use data to fit hypothesis
- Good experiments = have replication, measure variability, generalize problem, transparent
- Prediction is not inference, and be ware of data dredging